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Fertil Steril. 2017 Jan;107(1):83-88.e2. doi: 10.1016/j.fertnstert.2016.09.035. Epub 2016 Oct 25.

Decline in semen quality among 30,636 young Chinese men from 2001 to 2015.

Author information

1
Institute of Reproductive and Stem Cell Engineering, Basic Medicine College, Central South University, Changsha, Hunan, People's Republic of China.
2
Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, Hunan, People's Republic of China.
3
Institute of Reproductive and Stem Cell Engineering, Basic Medicine College, Central South University, Changsha, Hunan, People's Republic of China; Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, Hunan, People's Republic of China.
4
Institute of Reproductive and Stem Cell Engineering, Basic Medicine College, Central South University, Changsha, Hunan, People's Republic of China; Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, Hunan, People's Republic of China. Electronic address: zhuwenbing0971@sina.com.

Abstract

OBJECTIVE:

To provide information of semen quality among young Chinese men in the past 15 years.

DESIGN:

Retrospective cross-sectional study.

SETTING:

Sperm bank.

PATIENT(S):

A total of 30,636 young adult men who applied to be sperm donors at the Hunan Province Human Sperm Bank of China in 2001-2015 were included in the study.

INTERVENTION(S):

Physical examination and analysis of blood and semen samples.

MAIN OUTCOME MEASURE(S):

Semen parameters, such as semen volume, sperm concentration, total sperm count, progressively motile sperm count, sperm progressive motility, sperm morphology, and round cells.

RESULT(S):

Many of the semen parameters showed a decreasing trend over the 15-year observation period. The sperm concentration and percentage of sperm with normal morphology decreased from 68 × 106/mL to 47 × 106/mL and from 31.8% to 10.8%, respectively. Although sperm progressive motility showed irregular variation, the progressively motile sperm count decreased from 34 × 106 to 21 × 106 over the 15-year period. Furthermore, the rate of qualified donors fell from 55.78% in 2001 to 17.80% in 2015, and the rate for 2015 was approximately threefold lower than the corresponding rates in 2001.

CONCLUSION(S):

The semen quality among young Chinese men has declined over a period of 15 years, especially in terms of sperm concentration, total sperm count, sperm progressive motility, and normal morphology.

KEYWORDS:

Chinese young men; semen parameters; semen quality

[Indexed for MEDLINE]

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