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Interv Neurol. 2016 Sep;5(3-4):148-156. Epub 2016 Jun 28.

Treatment Strategies for Acute Ischemic Stroke Caused by Carotid Artery Occlusion.

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Department of Neurology, Jinling Hospital, Southern Medical University, Nanjing, China.


Background: Acute ischemic stroke caused by internal carotid artery (ICA) occlusion usually has a poor prognosis, especially the T occlusion cases without functional collaterals. The efficacy of intravenous (IV) or intra-arterial (IA) thrombolysis with recombinant tissue plasminogen activator (rt-PA) remains ambiguous in these patients. Eendovascular recanalization of the occluded carotid has been attempted in recent years as a potential strategy. However, the different etiologies of ICA occlusion pose a significant challenge to neurointerventionists. Recently, several endovascular evolvements have been reported in treating carotid occlusion-related stroke. This review summarizes the current status of treatment for acute ICA occlusion.


Acute ischemic stroke; Carotid artery occlusion; Intra-arterial therapy; Intravenous thrombolysis

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