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Nitric Oxide. 2016 Dec 30;61:55-61. doi: 10.1016/j.niox.2016.10.006. Epub 2016 Oct 21.

Dietary nitrate supplementation improves sprint and high-intensity intermittent running performance.

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Sport and Health Sciences, University of Exeter, Heavitree Road, Exeter, UK.
NIHR Exeter Clinical Research Facility, University of Exeter, Heavitree Road, Exeter, UK.
Gatorade Sports Science Institute, PepsiCo R&D, Barrington, IL, USA.
Sport and Health Sciences, University of Exeter, Heavitree Road, Exeter, UK. Electronic address:


The influence of dietary nitrate (NO3-) supplementation on indices of maximal sprint and intermittent exercise performance is unclear.


To investigate the effects of NO3- supplementation on sprint running performance, and cognitive function and exercise performance during the sport-specific Yo-Yo Intermittent Recovery level 1 test (IR1).


In a double-blind, randomized, crossover study, 36 male team-sport players received NO3--rich (BR; 70 mL·day-1; 6.4 mmol of NO3-), and NO3--depleted (PL; 70 mL·day-1; 0.04 mmol NO3-) beetroot juice for 5 days. On day 5 of supplementation, subjects completed a series of maximal 20-m sprints followed by the Yo-Yo IR1. Cognitive tasks were completed prior to, during and immediately following the Yo-Yo IR1.


BR improved sprint split times relative to PL at 20 m (1.2%; BR 3.98 ± 0.18 vs. PL 4.03 ± 0.19 s; P < 0.05), 10 m (1.6%; BR 2.53 ± 0.12 vs. PL 2.57 ± 0.19 s; P < 0.05) and 5 m (2.3%; BR 1.73 ± 0.09 vs. PL 1.77 ± 0.09 s; P < 0.05). The distance covered in the Yo-Yo IR1 test improved by 3.9% (BR 1422 ± 502 vs. PL 1369 ± 505 m; P < 0.05). The reaction time to the cognitive tasks was shorter in BR (615 ± 98 ms) than PL (645 ± 120 ms; P < 0.05) at rest but not during the Yo-Yo IR1. There was no difference in response accuracy.


Dietary NO3- supplementation enhances maximal sprint and high-intensity intermittent running performance in competitive team sport players. Our findings suggest that NO3- supplementation has the potential to improve performance in single-sprint or multiple-sprint (team) sports.


Beetroot juice; Cognitive performance; Nitric oxide; Running speed

[Indexed for MEDLINE]

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