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Abdom Radiol (NY). 2017 Mar;42(3):870-876. doi: 10.1007/s00261-016-0948-8.

Multiple arterial phase MRI of arterial hypervascular hepatic lesions: improved arterial phase capture and lesion enhancement.

Author information

1
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, 505 Parnassus Avenue, M391, CA, 94143-0628, USA.
2
Department of Radiology, San Francisco Veteran Affairs Medical Center, San Francisco, CA, USA.
3
Department of Surgery, University of California San Francisco, San Francisco, CA, USA.
4
Department of Medicine, San Francisco Veteran Affairs Medical Center, San Francisco, CA, USA.
5
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, 505 Parnassus Avenue, M391, CA, 94143-0628, USA. thomas.hope@ucsf.edu.
6
Department of Radiology, San Francisco Veteran Affairs Medical Center, San Francisco, CA, USA. thomas.hope@ucsf.edu.

Abstract

PURPOSE:

To establish if triple-phase arterial imaging improves the detection of arterial phase hyperintense lesions based on arterial phase capture, motion artifact degradation, and lesion enhancement when compared to single-phase imaging.

MATERIALS AND METHODS:

Patients at risk for hepatocellular carcinoma were imaged at 3.0T. Seventy-three consecutive patients with a standard single-phase MRI and eighty-five consecutive patients were imaged using extracellular contrast with triple arterial phase MRI using three sequential accelerated acquisitions of 8 s. Arterial phase capture and image quality were qualitatively categorized. Forty single-phase and forty-four triple-phase studies contained arterially enhancing lesions > 1 cm with washout appearance. The contrast-to-noise ratio (CNR) of the lesions was calculated. We compared the differences in means with Student t-tests and those in arterial phase capture with a Chi squared test with Yates correction.

RESULTS:

The triple-phase acquisitions captured the early or late arterial phases more frequently than did the single-phase acquisition (99% vs 86%; P value = 0.006). Triple-phase also provided greater number of patients with early or late arterial phase imaging without motion artifact (92% vs 79%, P-value = 0.05). The lesion analysis revealed increased maximum CNR in the triple-phase imaging (704.4) vs. single-phase imaging (517.2), P-value < 0.001.

CONCLUSION:

Triple-phase acquisition provides more robust arterial phase imaging for hepatic lesions, with increased lesion CNR, compared to standard single-phase arterial phase imaging.

KEYWORDS:

Arterial phase imaging; Hepatocellular carcinoma; Liver MRI; Respiratory motion

PMID:
27770162
PMCID:
PMC5357156
DOI:
10.1007/s00261-016-0948-8
[Indexed for MEDLINE]
Free PMC Article

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