Format

Send to

Choose Destination
Minerva Gastroenterol Dietol. 2017 Mar;63(1):62-73. doi: 10.23736/S1121-421X.16.02345-X. Epub 2016 Oct 21.

Update on hepatitis C treatment: systematic review of clinical trials.

Author information

1
Liver Care Network and Organ Care Research, Swedish Medical Center, Seattle, WA, USA.
2
Liver Care Network and Organ Care Research, Swedish Medical Center, Seattle, WA, USA - kris.kowdley@swedish.org.

Abstract

Chronic hepatitis C is a major public health problem. The chronicity of the hepatitis C can lead to advanced liver disease, cirrhosis and even hepatocellular carcinoma. Chronic hepatitis C is the leading indication of for liver transplantation in the United States. Since the introduction of directly acting antiviral agents (DAAs), there have been there have been dramatic advances in treatment of hepatitis C in terms of tolerability, duration of therapy with significant increases in the rates of sustained virologic response (SVR). This review summarizes the findings of recently published clinical trials of DAAs in the treatment of hepatitis C by genotype and in patients co-infected with HCV/HIV.

PMID:
27768010
DOI:
10.23736/S1121-421X.16.02345-X
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Minerva Medica
Loading ...
Support Center