Format

Send to

Choose Destination
J Clin Pharm Ther. 2017 Apr;42(2):128-131. doi: 10.1111/jcpt.12466. Epub 2016 Oct 18.

Comparison of open-access vancomycin dosing websites.

Author information

1
Department of Veterans Affairs, Central Texas Veterans Health Care System, Temple, TX, USA.

Abstract

WHAT IS KNOWN AND OBJECTIVE:

There are many methods for dosing vancomycin. The purpose of this commentary was to compare open-access vancomycin dosing websites with Vancomycin-Calculator.com and describe how body weight can affect their pharmacokinetic (PK) calculations.

COMMENT:

A vancomycin dosing website, Vancomycin-Calculator.com, was developed to improve the dosing practice at our health system. Nine other vancomycin dosing calculators were identified, including three open-access websites. Each website uses a different dosing method. Most of the websites calculated similar doses for patients with normal body weight. Vancomycin-Calculator.com was the only website to calculate practical doses for obese patients, and it calculated higher daily doses for underweight patients compared to other websites.

WHAT IS NEW AND CONCLUSION:

Vancomycin-Calculator.com is an open-access vancomycin dosing website that was developed using the Bauer PK method. Compared with three other websites, PK calculations resulted in significant differences for underweight and obese patients.

KEYWORDS:

Calculator; Dosing; Pharmacokinetics; Vancomycin; Website

PMID:
27757973
DOI:
10.1111/jcpt.12466
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center