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Clin Exp Rheumatol. 2016 Sep-Oct;34 Suppl 100(5):106-109. Epub 2016 Sep 29.

UK Scleroderma Study Group (UKSSG) guidelines on the diagnosis and management of scleroderma renal crisis.

Author information

1
Centre for Rheumatology, Royal Free London and UCL Division of Medicine, London, UK.
2
Department of Renal Medicine, Royal Free London NHS Foundation Trust, London, UK.
3
Centre for Rheumatology, Royal Free London and UCL Division of Medicine, London, UK. c.denton@ucl.ac.uk.

Abstract

The UK Scleroderma Study Group developed guidelines on the diagnosis and management of scleroderma renal crisis (SRC) based on best available evidence and clinical experience. SRC is characterised by the acute onset of severe hypertension and acute kidney injury. Current strategies to reduce the associated morbidity and mortality include identifying at risk patients to aid early diagnosis. ACE inhibitor therapy should be lifelong in all patients, regardless of whether they require renal replacement therapy. Patients with SRC may recover renal function up to 3 years after the crisis, most often within 12 to 18 months.

PMID:
27749244
[Indexed for MEDLINE]

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