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Med Clin North Am. 2016 Nov;100(6):1341-1356. doi: 10.1016/j.mcna.2016.06.012. Epub 2016 Sep 13.

Nutrition Interventions for Obesity.

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Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, NC, USA. Electronic address:
Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC, USA.
Department of Health Policy and Management, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.


Obesity is a common disorder with complex causes. The epidemic has spurred significant advances in the understanding of nutritional approaches to treating obesity. Although the primary challenge is to introduce a dietary intake that creates an energy deficit, clinicians should also consider targeted risk factor modification with manipulation of the nutrient profile of the weight-reducing diet. These strategies produce significant weight loss and improvements in cardiometabolic risk factors. Future research is needed to better understand how to personalize nutrient prescriptions further to promote optimal risk modification and maintenance of long-term energy balance in the weight-reduced state.


Dietary therapy; Energy balance; Maintenance of weight loss; Obesity; Weight loss; Weight-reducing diet

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