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J Endovasc Ther. 2017 Feb;24(1):149-155. doi: 10.1177/1526602816674455. Epub 2016 Oct 15.

Midterm Outcome of Mechanochemical Endovenous Ablation for the Treatment of Great Saphenous Vein Insufficiency.

Author information

1
1 Department of Surgery, Rijnstate Hospital, Arnhem, the Netherlands.
2
2 Department of Surgery, Antonius Hospital, Nieuwegein, the Netherlands.
3
3 Department of Surgery, Division of Vascular Surgery, University Medical Center Groningen, University of Groningen, the Netherlands.

Abstract

PURPOSE:

To report the midterm results of mechanochemical ablation (MOCA) for treating great saphenous vein (GSV) insufficiency.

METHODS:

In a 1-year period, 85 consecutive patients (median age 51.4 years; 71 women) undergoing MOCA with polidocanol in 104 limbs were enrolled in a prospective registry. The patients were evaluated at baseline and during follow-up (4 weeks and 1, 2, and 3 years) using duplex ultrasound, the CEAP (clinical, etiologic, anatomic and pathophysiologic) classification, the Venous Clinical Severity Score (VCSS), the RAND Short Form 36-Item Health Survey (RAND-SF36), and the Aberdeen Varicose Vein Questionnaire (AVVQ). Primary outcome measures were clinical and anatomic success. Secondary outcome measures included general and disease-specific quality of life and reinterventions.

RESULTS:

Technical success (99%) was achieved in all but 1 patient in whom technical problems with the device led to conversion to another method for treatment of 2 limbs. After a median follow-up of 36 months (interquartile range 12.5, 46.3), recanalization occurred in 15 (15%) of 102 successfully treated vein segments. Anatomic success was 92%, 90%, and 87% after 1, 2, and 3 years, respectively. The VCSS improved at all time intervals compared to the preprocedure median. The clinical success at 3 years was 83%. The AVVQ and RAND-SF36 scores showed an improvement at all time intervals compared to baseline values. Between 12 and 36 months, however, a significant deterioration was observed in VCSS, which was accompanied by worsening of disease-specific and general quality of life.

CONCLUSION:

In the longest follow-up of MOCA to date, this study shows MOCA to be an effective treatment modality for GSV insufficiency at midterm follow-up, but clinical results seem to drop over time.

KEYWORDS:

great saphenous vein; mechanochemical occlusion; polidocanol; varicose vein; venous insufficiency

PMID:
27742900
DOI:
10.1177/1526602816674455
[Indexed for MEDLINE]

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