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Curr Opin Neurobiol. 2016 Dec;41:174-178. doi: 10.1016/j.conb.2016.09.013. Epub 2016 Oct 11.

Cortical circuits and modules in movement generation: experiments and theories.

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Dept of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address:
McGovern Institute and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, United States.


Here we review recent studies of the cortical circuits subserving the control of posture and movement. This topic is addressed from neurophysiological and evolutionary perspectives describing recent advancements achieved through experimental studies in humans and non-human primates. We also describe current debates and controversies concerning motor mapping within the motor cortex and the different computational approaches aimed at resolving the mystery around motor representations and computations. In recent years there is growing interest in the possibly modular organization of motor representations and dynamical processes and the potential of such studies to provide new clues into motor information processing. Hence this review focuses on motor modularity, highlighting the new research directions inspired by empirical findings and theoretical models developed within the last several years.

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