Format

Send to

Choose Destination
J Hum Nutr Diet. 2017 Jun;30(3):260-274. doi: 10.1111/jhn.12431. Epub 2016 Oct 11.

Food-based anthocyanin intake and cognitive outcomes in human intervention trials: a systematic review.

Author information

1
School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, Australia.
2
Centre for Nutrition and Food Sciences, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, QLD, Australia.
3
Department of Agriculture and Fisheries, Queensland Government, Brisbane, QLD, Australia.

Abstract

BACKGROUND:

Preclinical evidence suggests that the anthocyanins, which comprise a subclass of dietary flavonoids providing the purple and red pigmentation in plant-based foods, may have a beneficial impact on cognitive outcomes.

METHODS:

A systematic review was conducted to identify the published literature on food-based anthocyanin consumption and cognitive outcomes in human intervention trials. The literature search followed PRISMA guidelines and included six databases, as well as additional hand searching.

RESULTS:

Seven studies were included in this review, comprising acute trials (n = 4) and longer-term (n = 3) interventions that assessed multiple cognitive outcomes in children, adults and older adults with cognitive impairment. Six of seven studies reported improvements in either a single, or multiple, cognitive outcomes, including verbal learning and memory, after anthocyanin-rich food consumption. As a result of methodological limitations and the large clinical and methodological diversity of the studies, the pooling of data for quantitative analysis was not feasible.

CONCLUSIONS:

The impact of food-based anthocyanin consumption on both acute and long-term cognition appears promising. However, adequately powered studies that include sensitive cognitive tasks are needed to confirm these findings and allow the translation of research into dietary messages.

KEYWORDS:

anthocyanins; cognition; flavonoids; polyphenols

PMID:
27730693
DOI:
10.1111/jhn.12431
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center