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Orbit. 2016 Dec;35(6):357-359. Epub 2016 Aug 12.

Aggressive esthesioneuroblastoma with divergent differentiation: A taxonomic dilemma.

Author information

1
a Department of Ophthalmology , New York University Langone Medical Center , New York , New York , USA.
2
b Department of Pathology , New York University Langone Medical Center , New York , New York , USA.

Abstract

The authors describe an esthesioneuroblastoma (olfactory neuroblastoma) that occurred within the nasal cavity and brain in a 31-year-old man. Following excision, the tumor recurred in the left orbit and in mediastinal lymph nodes. Treatment included orbital excision and systemic chemotherapy. Histopathology showed a high-grade neuroepithelial tumor with positive immunohistochemical markers for neuroendocrine and epithelial components, an unusual combination raising issues concerning taxonomy.

KEYWORDS:

Esthesioneuroblastoma; olfactory neuroblastoma

PMID:
27715372
DOI:
10.1080/01676830.2016.1193537
[Indexed for MEDLINE]

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