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  • PMID: 27694197 was deleted because it is a duplicate of PMID: 28171531
Bioinformatics. 2017 Feb 1;33(3):467-469. doi: 10.1093/bioinformatics/btw630.

Pro54DB: a database for experimentally verified sigma-54 promoters.

Author information

Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology and Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu, China.
Department of Pathophysiology, Southwest Medical University, Luzhou, China.
Department of Physics, School of Sciences, Center for Genomics and Computational Biology, North China University of Science and Technology, Tangshan, China.



In prokaryotes, the σ54 promoters are unique regulatory elements and have attracted much attention because they are in charge of the transcription of carbon and nitrogen-related genes and participate in numerous ancillary processes and environmental responses. All findings on σ54 promoters are favorable for a better understanding of their regulatory mechanisms in gene transcription and an accurate discovery of genes missed by the wet experimental evidences. In order to provide an up-to-date, interactive and extensible database for σ54 promoter, a free and easy accessed database called Pro54DB (σ54 promoter database) was built to collect information of σ54 promoter. In the current version, it has stored 210 experimental-confirmed σ54 promoters with 297 regulated genes in 43 species manually extracted from 133 publications, which is helpful for researchers in fields of bioinformatics and molecular biology.

Availability and Implementation:

Pro54DB is freely available on the web at with all major browsers supported.

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[Indexed for MEDLINE]

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