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  • PMID: 27694197 was deleted because it is a duplicate of PMID: 28171531
Bioinformatics. 2017 Feb 1;33(3):467-469. doi: 10.1093/bioinformatics/btw630.

Pro54DB: a database for experimentally verified sigma-54 promoters.

Author information

1
Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology and Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu, China.
2
Department of Pathophysiology, Southwest Medical University, Luzhou, China.
3
Department of Physics, School of Sciences, Center for Genomics and Computational Biology, North China University of Science and Technology, Tangshan, China.

Abstract

Summary:

In prokaryotes, the σ54 promoters are unique regulatory elements and have attracted much attention because they are in charge of the transcription of carbon and nitrogen-related genes and participate in numerous ancillary processes and environmental responses. All findings on σ54 promoters are favorable for a better understanding of their regulatory mechanisms in gene transcription and an accurate discovery of genes missed by the wet experimental evidences. In order to provide an up-to-date, interactive and extensible database for σ54 promoter, a free and easy accessed database called Pro54DB (σ54 promoter database) was built to collect information of σ54 promoter. In the current version, it has stored 210 experimental-confirmed σ54 promoters with 297 regulated genes in 43 species manually extracted from 133 publications, which is helpful for researchers in fields of bioinformatics and molecular biology.

Availability and Implementation:

Pro54DB is freely available on the web at http://lin.uestc.edu.cn/database/pro54db with all major browsers supported.

Contacts:

greatchen@ncst.edu.cn or hlin@uestc.edu.cn

PMID:
28171531
DOI:
10.1093/bioinformatics/btw630
[Indexed for MEDLINE]

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