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Can J Cardiol. 2016 Oct;32(10 Suppl 2):S388-S396. doi: 10.1016/j.cjca.2016.07.006. Epub 2016 Jul 18.

Evaluation of Cardiac, Vascular, and Skeletal Muscle Function With MRI: Novel Physiological End Points in Cardiac Rehabilitation Research.

Author information

1
Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada. Electronic address: richard.thompson@ualberta.ca.
2
College of Kinesiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
3
College of Nursing and Health Innovation, University of Texas at Arlington, Arlington, Texas, USA.

Abstract

Impaired exercise tolerance is a major determinant of decreased quality of life and survival in individuals with cardiovascular disease. The relative contribution that abnormal cardiac, vascular, and skeletal muscle function plays in limiting exercise tolerance and its improvement with exercise training in patients with cardiovascular disease is not fully known. In this review, we provide an overview of the functional impairment of these systems as they relate to exercise capacity and the emerging role of magnetic resonance imaging as a comprehensive tool to evaluate mechanisms that may explain exercise intolerance.

PMID:
27692120
DOI:
10.1016/j.cjca.2016.07.006
[Indexed for MEDLINE]

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