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J Saudi Heart Assoc. 2016 Oct;28(4):274-7. doi: 10.1016/j.jsha.2016.02.003. Epub 2016 Feb 15.

All that looks like "Brugada" is not "Brugada": Case series of Brugada phenocopy caused by hyponatremia.

Author information

1
Department of Internal Medicine/Pediatrics and Internal Medicine, Western Michigan University, Homer Stryker School of Medicine, Kalamazoo, MI, aUSA.
2
Department of Cardiology. Borgess Medical Center/Michigan State University, Kalamazoo, MI, bUSA.

Abstract

Brugada syndrome (BS), a life-threatening channelopathy associated with reduced inward sodium current due to dysfunctional sodium channels, is characterized by ST-segment elevation with downsloping "coved type" (type 1) or "saddle back" (type 2) pattern in V1-V3 precordial chest leads (1, 2). Brugada phenocopy, a term describing conditions inducing Brugada-like pattern of electrocardiogram (EKG) manifestations in patients without true BS, is an emerging condition (3). We describe a case series of Brugada phenocopy with hyponatremia.

KEYWORDS:

Brugada syndrome; Electrocardiogram; Hyponatremia

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