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Int J Cardiol. 1989 Aug;24(2):159-64.

Analysis of survival in patients with pulmonary atresia and intact ventricular septum treated surgically.

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Department of Pediatrics, University of Toronto Faculty of Medicine, Ontario, Canada.


The epidemiology of 98 children who underwent surgical intervention for pulmonary atresia and intact ventricular septum is presented. Sixty-one (62.2%) of the children died. Survival time from the date of the first operation ranged from 0 to 17.76 years. Analysis of the survivors revealed that an estimate of the probability of surviving for two years is 47% (95% confidence limits of 37%, 57%). An estimate of the median survival time is 1.43 years. In a Cox proportional hazards model, using survival time in days as the outcome variable (n = 73, using complete data), operative weight at first operation (P = 0.0019), right/left ventricular pressure ratio (P = 0.0185), and absence of ventriculo-coronary arterial connections (P = 0.0362) were identified as significant predictors of survival.

[Indexed for MEDLINE]

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