Gut microbiota signatures of longevity

Curr Biol. 2016 Sep 26;26(18):R832-R833. doi: 10.1016/j.cub.2016.08.015.

Abstract

An aging global population poses substantial challenges to society [1]. Centenarians are a model for healthy aging because they have reached the extreme limit of life by escaping, surviving, or delaying chronic diseases [2]. The genetics of centenarians have been extensively examined [3], but less is known about their gut microbiotas. Recently, Biagi et al.[4] characterized the gut microbiota in Italian centenarians and semi-supercentenarians. Here, we compare the gut microbiota of Chinese long-living people with younger age groups, and with the results from the Italian population [4], to identify gut-microbial signatures of healthy aging.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aging*
  • China
  • Female
  • Gastrointestinal Microbiome*
  • Humans
  • Italy
  • Longevity*
  • Male
  • Middle Aged
  • Young Adult