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Circ Cardiovasc Genet. 2016 Oct;9(5):448-467. Epub 2016 Sep 26.

Enhancing Literacy in Cardiovascular Genetics: A Scientific Statement From the American Heart Association.

Abstract

Advances in genomics are enhancing our understanding of the genetic basis of cardiovascular diseases, both congenital and acquired, and stroke. These advances include finding genes that cause or increase the risk for childhood and adult-onset diseases, finding genes that influence how patients respond to medications, and the development of genetics-guided therapies for diseases. However, the ability of cardiovascular and stroke clinicians to fully understand and apply this knowledge to the care of their patients has lagged. This statement addresses what the specialist caring for patients with cardiovascular diseases and stroke should know about genetics; how they can gain this knowledge; how they can keep up-to-date with advances in genetics, genomics, and pharmacogenetics; and how they can apply this knowledge to improve the care of patients and families with cardiovascular diseases and stroke.

KEYWORDS:

AHA Scientific Statements; aneurysm; arrhythmia; cardiomyopathy; channelopathy; congenital heart defects; genetic testing; genetics; pharmacogenetics; pharmacology

PMID:
27672144
DOI:
10.1161/HCG.0000000000000031
[Indexed for MEDLINE]

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