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Appl Opt. 2016 Sep 10;55(26):7212-7. doi: 10.1364/AO.55.007212.

High-resolution, dual-depth spectral-domain optical coherence tomography with interlaced detection for whole-eye imaging.


Dual-depth spectral-domain optical coherence tomography (SD-OCT) enables high-resolution in vivo whole-eye imaging. Two orthogonally polarized beams from a source are focused simultaneously on two axial positions of the anterior segment and the retina. For the detector arm, a 1×2 ultrafast optical switch sequentially delivers two spectral interference signals to a single spectrometer, which extends the in-air axial depth range up to 9.44 mm. An off-pivot complex conjugate removal technique doubles the depth range for all anterior segment imaging. The graphics-processing-unit-based parallel signal processing algorithm supports fast two- and three-dimensional image displays. The obtained high-resolution anterior and retinal images are measured biometrically. The dual-depth SD-OCT system has an axial resolution of ∼6.4  μm in air, and the sensitivity is 91.79 dB at 150 μm from the zero-delay line.

[Indexed for MEDLINE]

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