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Springerplus. 2016 Sep 13;5(1):1551. doi: 10.1186/s40064-016-3236-8. eCollection 2016.

Is it bowel-associated dermatosis-arthritis syndrome induced by small intestinal bacteria overgrowth?

Author information

  • 1Department of Rheumatology and Immunology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan Province 410008 People's Republic of China.
  • 2Departments of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008 People's Republic of China.

Abstract

INTRODUCTION:

Bowel-associated dermatosis-arthritis syndrome is rare systemic diseases characterized by a prodrome of fever, chills, and influenza-like symptoms with subsequent skin eruptions, myalgias, and polyarthralgias. It is reported to be occurred in Intestinal bypass surgery and inflammatory bowel disease.

CASE DESCRIPTION:

Herein, we described a 29-years-old man with Bowel-associated dermatosis-arthritis syndrome. He had no history of gastrointestinal surgery and inflammatory bowel disease. Distribution of the gut bacterial flora showed small intestinal bacterial overgrowth.

DISCUSSION AND EVALUATION:

It is rarely form as Non-intestinal bypass road and non-inflammatory bowel disease was induced by small intestinal bacteria overgrowth.

CONCLUSIONS:

We concluded that Immuno-inflammatory response to overgrowth of intestinal bacterial antigen induce the clinical symptoms of bowel-associated dermatosis-arthritis syndrome.

KEYWORDS:

Arthritis; Dermatosis; Inflammatory bowel disease

PMID:
27652124
PMCID:
PMC5021650
DOI:
10.1186/s40064-016-3236-8
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