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J Asian Nat Prod Res. 2017 May;19(5):462-467. doi: 10.1080/10286020.2016.1234458. Epub 2016 Sep 21.

Two new C-glucosyl flavonoids from Ziziphus jujube and their anti-inflammatory activity.

Author information

1
a School of Pharmacy and Bioengineering , Chengdu University , Chengdu 610106 , China.
2
b School of Biology Sciences and Food Technology , Hanshan Normal University , Chaozhou 521041 , China.

Abstract

Two new C-glucosyl flavonoids 6''-O-feruloylspinosin and 6''-O-feruloyl-6'''-p-hydroxybenzoylspinosin, together with five known compounds, were isolated from the seeds of Ziziphus jujube (Rhamnaceae family). Their structures were elucidated on the basis of chemical and spectroscopic evidences. Compounds 1-7 showed moderate inhibitory effects against COX-1 and COX-2 enzymes.

KEYWORDS:

C-glucosyl flavonoids; COX inhibiting activity; Rhamnaceae; Ziziphus jujube

PMID:
27649580
DOI:
10.1080/10286020.2016.1234458
[Indexed for MEDLINE]

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