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Trends Cell Biol. 2016 Nov;26(11):818-824. doi: 10.1016/j.tcb.2016.08.005. Epub 2016 Sep 14.

The Future of Cell Biology: Emerging Model Organisms.

Author information

1
Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: bobg@email.unc.edu.
2
Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: nicoleking.ucb@gmail.com.

Abstract

Most current research in cell biology uses just a handful of model systems including yeast, Arabidopsis, Drosophila, Caenorhabditis elegans, zebrafish, mouse, and cultured mammalian cells. And for good reason - for many biological questions, the best system for the question is likely to be found among these models. However, in some cases, and particularly as the questions that engage scientists broaden, the best system for a question may be a little-studied organism. Modern research tools are facilitating a renaissance for unusual and interesting organisms as emerging model systems. As a result, we predict that an ever-expanding breadth of model systems may be a hallmark of future cell biology.

PMID:
27639630
PMCID:
PMC5077642
DOI:
10.1016/j.tcb.2016.08.005
[Indexed for MEDLINE]
Free PMC Article

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