Novel one-pot reaction conditions have been developed for the preparation of glycosyl thiourea derivatives directly from glycosyl azides mediated by a combination of sulfamic acid and sodium iodide. The reaction conditions were clean, non-toxic and the products were isolated in good to excellent yield.
Keywords: Azide; Carbohydrate; Isothiocyanate; Reduction; Sodium iodide; Sulfamic acid; Thiourea.
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