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Womens Health (Lond). 2016 Jul;12(4):427-32. doi: 10.1177/1745505716653691.

Diabetes prevention: Reproductive age women affected by insulin resistance.

Author information

1
Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Weill Cornell Medical College, New York, NY, USA.
2
School of Medicine, St. George's University, Grenada, West Indies.
3
Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Weill Cornell Medical College, New York, NY, USA Cassandra.henderson@nychhc.org.

Abstract

In the United States, 29.1 million people are affected by diabetes, of which 95% have type 2 diabetes. There has been a fivefold increase in type 2 diabetes in the latter half of the 20th century, an increase strongly linked to the obesity epidemic in the United States. In addition, insulin resistance affects 86 million Americans, or more than one-third of the adult population, as manifested by impaired fasting glucose tolerance with random glucose values ranging from ⩾100 to <126 mg/dL. In all, 90% of those affected by impaired fasting glucose tolerance or pre-diabetes are unaware of their metabolic derangement. Although impaired fasting glucose tolerance increases one's risk of developing type 2 diabetes, once identified, application of lifestyle changes by affected individuals may avoid or delay the onset of type 2 diabetes. For reproductive age women who are found to have impaired fasting glucose tolerance, lifestyle changes may be an effective tool to diminish the reproductive health consequences of insulin resistance related diseases.

KEYWORDS:

Lifestyle changes; diabetes prevention; gestational diabetes; insulin resistance; medical nutrition therapy; preconception counseling; pregnancy; reproductive age women; type 2 diabetes mellitus

PMID:
27638898
PMCID:
PMC5373272
DOI:
10.1177/1745505716653691
[Indexed for MEDLINE]
Free PMC Article

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