New diagnosis of rheumatoid arthritis during the third trimester of pregnancy

Womens Health (Lond). 2016 Jul;12(4):407-11. doi: 10.1177/1745505716661724.

Abstract

We report here an unusual case of rheumatoid arthritis presenting for the first time in a 32-week pregnant patient. Despite thorough evaluations from different specialties, the patient's diagnosis went undiscovered originally being attributed to orthopedic issues and then to normal symptoms of pregnancy. The patient's symptoms progressively worsened until she was no longer able to ambulate and complete her daily activities. A primary diagnosis of rheumatoid arthritis is exceedingly rare during pregnancy due to changes in the body's immune system that accommodate the foreign fetus. Also physiologic changes that occur during pregnancy can often cloud the clinical picture of a patient presenting with joint pain and weakness. Nonetheless, a thorough workup should be conducted to rule out underlying rheumatologic disease.

Keywords: autoimmune disorder; cholestasis of pregnancy; pregnancy; rheumatoid arthritis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Arthritis, Rheumatoid / diagnosis*
  • Arthritis, Rheumatoid / physiopathology*
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications / diagnosis*
  • Pregnancy Complications / physiopathology*
  • Pregnancy Outcome
  • Pregnancy Trimester, Third*