Cytologic and biochemical examination of the subretinal fluid in diagnosis of Coats' disease

Acta Ophthalmol (Copenh). 1989 Jun;67(3):342-6. doi: 10.1111/j.1755-3768.1989.tb01885.x.

Abstract

Two babies presenting with unilateral leukocoria were found to have total retinal detachment in one eye, associated with subretinal yellowish-white deposits. As no calcification was found and subretinal fluid aspiration yielded many fat-laden macrophages without any evidence of retinoblastoma cells in addition to a high level of cholesterol, the difinitive diagnosis of Coats' disease was made. Subsequently, retinal detachment surgery and cryotherapy were performed, in an attempt to preserve the affected eye.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Infant
  • Macrophages / pathology
  • Male
  • Photography
  • Retinal Detachment / pathology
  • Retinal Diseases / congenital
  • Retinal Diseases / immunology
  • Retinal Diseases / pathology
  • Retinal Vessels / abnormalities*
  • Retinal Vessels / pathology