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Healthc (Amst). 2016 Sep;4(3):138-41. doi: 10.1016/j.hjdsi.2015.07.005. Epub 2015 Jul 29.

Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems.

Author information

1
Group Health Research Institute, Seattle, WA, USA.
2
Kaiser Permanente Center for Health Research, Portland, OR, USA.
3
University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
4
Hawaii Permanente Medical Group, Mililani, HI, USA.
5
University of California Irvine School of Medicine, Irvine CA, USA.
6
University of Washington, Seattle, WA, USA.
7
OCHIN, Portland, OR USA.
8
Clinical Services Group, Hospital Corporation of America, Nashville, TN, USA.
9
Group Health Research Institute, Seattle, WA, USA. Electronic address: johnson.ke@ghc.org.

Abstract

Pragmatic clinical trials are increasingly common because they have the potential to yield findings that are directly translatable to real-world healthcare settings. Pragmatic clinical trials need to integrate research into clinical workflow without placing an undue burden on the delivery system. This requires a research partnership between investigators and healthcare system representatives. This paper, organized as a series of case studies drawn from our experience in the NIH Health Care Systems Research Collaboratory, presents guidance from informational interviews of physician-scientists, health services researchers, and delivery system leaders who recently launched pragmatic clinical trials.

KEYWORDS:

Pragmatic trials

PMID:
27637816
PMCID:
PMC5027068
DOI:
10.1016/j.hjdsi.2015.07.005
[Indexed for MEDLINE]
Free PMC Article

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