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Diagn Cytopathol. 2017 Jan;45(1):66-68. doi: 10.1002/dc.23600. Epub 2016 Sep 15.

Cerebrospinal Fluid Cytological Diagnosis in Multiple Myeloma With Leptomeningeal Involvement: A Report of Two Cases.

Author information

1
Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.
2
Department of Neurology, the Second Hospital of Hebei Medical University, Shijiazhuang, 050000, China.
3
Department of Hemotology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.

Abstract

Multiple myeloma (MM) with central nervous system (CNS) infiltration is uncommon and the diagnosis is more complicated than that of MM. Here we report two cases of CNS MM that was diagnosed by cerebrospinal fluid cytology examination. Cerebrospinal fluid cytology examination can help to detect malignant cells and immunocytochemistry stain is of great value in identifying an unknown tumor. Diagn. Cytopathol. 2017;45:66-68.

KEYWORDS:

central nervous system; cerebrospinal fluid cytology; multiple myeloma

PMID:
27628930
DOI:
10.1002/dc.23600
[Indexed for MEDLINE]

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