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Am J Cardiol. 2016 Nov 1;118(9):1363-1367. doi: 10.1016/j.amjcard.2016.07.061. Epub 2016 Aug 12.

Usefulness of Psoas Muscle Area Determined by Computed Tomography to Predict Mortality or Prolonged Length of Hospital Stay in Patients Undergoing Left Ventricular Assist Device Implantation.

Author information

1
Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri.
2
Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri.
3
Division of Diagnostic Radiology, Washington University School of Medicine, St. Louis, Missouri.
4
Cardiology Division, Baylor University Medical Center, Dallas, Texas.
5
Florida Hospital Transplant Institute, Florida Hospital, Orlando, Florida.
6
Cardiology Division, Baylor University Medical Center, Dallas, Texas. Electronic address: susan.joseph@baylorhealth.edu.

Abstract

The purpose of this study is to examine the association of sarcopenia as measured by psoas muscle area and outcomes in patients undergoing left ventricular assist device (LVAD) implantation. We retrospectively examined 333 consecutive patients who underwent implantation of a HeartMate II LVAD at our institution from June 2008 to August 2013. Patients were included if they had a perioperative computed tomography that spanned the L3-L4 vertebrae. Sarcopenia was defined as having the lowest tertile psoas muscle area by gender. The primary end point was the composite of inpatient death or prolonged length of stay of >30 days. One hundred patients met inclusion criteria. The psoas muscle area cut-off values for the lowest tertiles were 12.0 cm2 for men and 6.5 cm2 for women, resulting in 32 sarcopenic patients (32%). The primary outcome of inpatient death or prolonged length of stay occurred in 81% of patients in the sarcopenic versus 60% in the nonsarcopenic group (p = 0.043). There was a trend toward prolonged length of stay in sarcopenic patients but no difference in overall mortality. This demonstrates that sarcopenia as measured by psoas muscle area is associated with increased composite length of stay and mortality after LVAD implantation and may serve as correlate for frailty.

PMID:
27622708
DOI:
10.1016/j.amjcard.2016.07.061
[Indexed for MEDLINE]

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