The complete sequence and genome organization of ligustrum virus A, a novel carlavirus

Arch Virol. 2016 Dec;161(12):3593-3596. doi: 10.1007/s00705-016-3054-x. Epub 2016 Sep 10.

Abstract

The complete genome sequence of ligustrum virus A (LVA) from a Ligustrum obtusifolium Sieb. & Zucc. plant was determined. The genomic RNA has 8,525 nucleotides, excluding the poly(A) tail, and consists of six open reading frames typical of members of the genus Carlavirus, family Betaflexiviridae. Phylogenetic analysis of the viral replicase and coat protein (CP) indicated that LVA is closely related to daphne virus S and helenium virus. The replicase and CP of LVA shared 44.73-52.35 % and 25.39-62.46 % amino acid identity, respectively, with those of other carlaviruses. These results suggest that LVA is a member of a distinct carlavirus species.

MeSH terms

  • Carlavirus / classification
  • Carlavirus / genetics*
  • Carlavirus / isolation & purification*
  • Cluster Analysis
  • Gene Order*
  • Genome, Viral*
  • Ligustrum / virology*
  • Open Reading Frames
  • Phylogeny
  • RNA, Viral / genetics*
  • Sequence Analysis, DNA*
  • Sequence Homology

Substances

  • RNA, Viral