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Mol Biol Evol. 2016 Dec;33(12):3158-3160. Epub 2016 Sep 9.

Paternal Mitochondrial Transmission in Intra-Species Caenorhabditis briggsae Hybrids.

Author information

1
Department of Biology, California State University, Fresno, CA jross@csufresno.edu.
2
Department of Integrative Biology, Oregon State University, Corvallis, OR.
3
Department of Biology, Portland State University, Portland, OR.
4
Institute of Ecology and Evolution, University of Oregon, Eugene, OR.

Abstract

To study mitochondrial-nuclear genetic interactions in the nematode Caenorhabditis briggsae, our three laboratories independently created 38 intra-species cytoplasmic-nuclear hybrid (cybrid) lines. Although the cross design combines maternal mitotypes with paternal nuclear genotypes, eight lines (21%) unexpectedly contained paternal mitotypes. All eight share in common ancestry of one of two genetically related strains. This unexpected parallel observation of paternal mitochondrial transmission, undesirable given our intent of creating cybrids, provides a serendipitous experimental model and framework to study the molecular and evolutionary basis of uniparental mitochondrial inheritance.

KEYWORDS:

coevolution; fertilization.; heteroplasmy; mitochondria; transmission

PMID:
27613821
PMCID:
PMC5100050
DOI:
10.1093/molbev/msw192
[Indexed for MEDLINE]
Free PMC Article

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