Format

Send to

Choose Destination
Trends Cardiovasc Med. 2017 Feb;27(2):136-140. doi: 10.1016/j.tcm.2016.07.006. Epub 2016 Aug 3.

Cardiovascular disease in patients with rheumatoid arthritis.

Author information

1
Division of Rheumatology, Immunology, and Allergy, Brigham and Women׳s Hospital, 75 Francis St, PBB-B3, Boston, MA 02115. Electronic address: kliao@partners.org.

Abstract

The risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA) is 1.5-2-fold higher than age- and sex-matched individuals from the general population. This excess risk is attributed to the systemic chronic inflammation which is a hallmark of RA. Challenges to optimizing CV risk management in RA include the need for improved methods to predict CV risk, and defining the target risk factor(s) to reduce CV risk. Lessons learned from RA studies can also inform CV risk prevention in the general population, where inflammation also has an important role in the pathogenesis of atherosclerosis.

KEYWORDS:

Cardiovascular disease; Inflammation; Lipids; Lipoproteins; Rheumatoid arthritis

PMID:
27612551
PMCID:
PMC5253086
DOI:
10.1016/j.tcm.2016.07.006
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center