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Clin Infect Dis. 2016 Dec 15;63(12):1622-1625. Epub 2016 Sep 6.

Fetal Infection by Zika Virus in the Third Trimester: Report of 2 Cases.

Author information

1
Department of Radiology, Faculdade de Medicina de São José do Rio Preto (FAMERP).
2
Hospital da Criança e Maternidade.
3
Laboratory of Virology, Department of Infectious and Dermatological Disease.
4
Department of Obstetrics and Gynecology.
5
Immunogenetics Laboratory, Department of Molecular Biology, FAMERP, São José do Rio Preto, São Paulo, Brazil.

Abstract

Zika virus (ZIKV) infection acquired during pregnancy is associated with congenital microcephaly. We describe 2 cases of ZIKV infection in women in their 36th week of pregnancy whose fetuses had preserved head circumference at birth and findings of subependymal cysts and lenticulostriate vasculopathy in postnatal imaging. These represent the first signs of congenital brain injury acquired due to ZIKV in the third trimester.

KEYWORDS:

Zika virus infection; central nervous system cysts; infection/congenital; lenticulostriate vasculopathy; ultrasonography

PMID:
27601223
DOI:
10.1093/cid/ciw613
[Indexed for MEDLINE]

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