Format

Send to

Choose Destination
See comment in PubMed Commons below
Genetics. 1989 Aug;122(4):915-22.

Genetic correlations and maternal effect coefficients obtained from offspring-parent regression.

Author information

1
Department of Ecology, University of Chicago, Illinois 60637.

Abstract

Additive genetic variances and covariances of quantitative characters are necessary to predict the evolutionary response of the mean phenotype vector in a population to natural or artificial selection. Standard formulas for estimating these parameters, from the resemblance between relatives in one or two characters at a time, are biased by natural selection on the parents and by maternal effects. We show how these biases can be removed using a multivariate analysis of offspring-parent regressions. A dynamic model of maternal effects demonstrates that, in addition to the phenotypic variance-covariance matrix of the characters, sufficient parameters for predicting the response of the mean phenotype vector to weak selection are the additive genetic variance-covariance matrix and a set of causal coefficients for maternal effects. These can be simultaneously estimated from offspring-parent regressions alone, in some cases just from the daughter-mother regressions, if all of the important selected and maternal characters have been measured and included in the analysis.

PMID:
2759429
PMCID:
PMC1203766
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center