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Acta Neurol Scand. 2017 Jan;135(1):4-16. doi: 10.1111/ane.12671. Epub 2016 Sep 1.

Alcohol withdrawal syndrome: mechanisms, manifestations, and management.

Author information

1
Department of Neurology, University Ulm, Ulm, Germany.
2
Department of Neurology and Clinical Neurophysiology, Trondheim University Hospital, Trondheim, Norway.
3
Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway.
4
Unit of Neurology, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
5
Danube University Krems, Krems, Austria.
6
Institute of Clinical Neuroscience and Neurophysiology, SU/Sahlgrenska Hospital, Gothenburg, Sweden.
7
Department of Neurology, Neurosurgery and Psychiatry, University of Medicine and Pharmacy Carol Davila, Colentina Hospital, Bucharest, Romania.
8
Academic Clinical Neurology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK.
9
Department of Neurology, Oulu University Hospital, Oulu, Finland.

Abstract

The alcohol withdrawal syndrome is a well-known condition occurring after intentional or unintentional abrupt cessation of heavy/constant drinking in patients suffering from alcohol use disorders (AUDs). AUDs are common in neurological departments with patients admitted for coma, epileptic seizures, dementia, polyneuropathy, and gait disturbances. Nonetheless, diagnosis and treatment are often delayed until dramatic symptoms occur. The purpose of this review is to increase the awareness of the early clinical manifestations of AWS and the appropriate identification and management of this important condition in a neurological setting.

KEYWORDS:

alcohol withdrawal; clinical management; delirium tremens; epileptic seizures; therapy

PMID:
27586815
PMCID:
PMC6084325
DOI:
10.1111/ane.12671
[Indexed for MEDLINE]
Free PMC Article

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