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J Diabetes Investig. 2016 Aug 31. doi: 10.1111/jdi.12573. [Epub ahead of print]

Where does liver fat go? A possible molecular link between fatty liver and diabetes.

Author information

  • 1Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan.
  • 2Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan. ttakamura@m-kanazawa.jp.

Abstract

An elevation of fatty acid delivery amplifies the TCA cycle flux with a rise in anaplerosis/cataplerosis, leading to a proportional rise in oxidative stress and inflammation in liver.

PMID:
27580368
DOI:
10.1111/jdi.12573
[PubMed - as supplied by publisher]
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