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BMC Ophthalmol. 2016 Aug 30;16(1):149. doi: 10.1186/s12886-016-0331-0.

Four-year observation of predictability and stability of small incision lenticule extraction.

Author information

1
Department of Ophthalmology and Vision Science, Eye and ENT Hospital of Fudan University, No.19 Baoqing Road, Xuhui District, Shanghai, China.
2
Aier School of Ophthalmology, Central South University, Changsha, China.
3
Department of Ophthalmology, UruTmqi Eye and ENT Hospital, No.387 Zhongshan Road, Urumqi, Xinjiang, China.
4
Department of Ophthalmology and Vision Science, Eye and ENT Hospital of Fudan University, No.19 Baoqing Road, Xuhui District, Shanghai, China. doctzhouxingtao@163.com.

Abstract

BACKGROUND:

To investigate long-term refractive outcomes, wavefront aberrations and quality of life after small incision lenticule extraction (SMILE) for moderate to high myopia.

METHODS:

A total of 26 patients (47 eyes) with preoperative mean spherical equivalent (SE) of -6.30 ± 1.47 diopters (D) who underwent SMILE were recruited. The measurements included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction, wavefront aberrations, and quality of life.

RESULTS:

At 4 years postoperatively, UDVA was better than or equal to 20/20 in 92 % of eyes. The efficacy index was 1.07 ± 0.16. 89 % of eyes were within ± 0.5 D of the intended refractive target. No eye lost any Snellen lines. The safety index was 1.16 ± 0.14. No significant changes of SE occurred among postoperative follow-ups at months 1, 3, 6 and years 1, 2, 4 (P > 0.05, Scheffe test). Higher-order aberrations, coma, spherical aberration and higher-order astigmatism increased postoperatively, and no significant changes of aberrations were detected among the 1-month, 6-month or 4-year follow-ups postoperatively (37 eyes). Compared to the spectacles group, the surgery group showed a significantly higher total score on quality of life (45.71 ± 2.61 vs 39.96 ± 3.56, P < 0.001).

CONCLUSIONS:

SMILE provides a predictable and stable correction of moderate to high myopia as documented by long-term follow-up.

KEYWORDS:

Aberrations; Quality of Life Impact of Refractive Correction (QIRC) questionnaire; Quality of life; Small incision lenticule extraction (SMILE)

PMID:
27577086
PMCID:
PMC5006606
DOI:
10.1186/s12886-016-0331-0
[Indexed for MEDLINE]
Free PMC Article

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