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Photomed Laser Surg. 2016 Oct;34(10):473-482. Epub 2016 Aug 29.

Pre-Exercise Infrared Low-Level Laser Therapy (810 nm) in Skeletal Muscle Performance and Postexercise Recovery in Humans, What Is the Optimal Dose? A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Author information

1
1 Laboratory of Phototherapy in Sports and Exercise, Universidade Nove de Julho (UNINOVE) , São Paulo, Brazil .
2
2 Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE) , São Paulo, Brazil .
3
3 Postgraduate Program in Biotechnology, University of Caxias do Sul , Caxias do Sul, Brazil .
4
4 Department of Pharmacology, University of São Paulo , São Paulo, Brazil .
5
5 Sports Medicine Institute, University of Caxias do Sul , Caxias do Sul, Brazil .
6
6 Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE) , São Paulo, Brazil .
7
7 Physiotherapy Research Group, Department of Global Public Health, Faculty of Medicine and Dentistry, University of Bergen , Bergen, Norway .

Abstract

AIM:

This study aimed to evaluate the medium-term effects of low-level laser therapy (LLLT or photobiomodulation) in postexercise skeletal muscle recovery and performance enhancement and to identify the optimal dose of 810 nm LLLT.

MATERIALS AND METHODS:

A randomized, double-blind, placebo-controlled trial was performed, with voluntary participation of 28 high-level soccer athletes. We analyzed maximum voluntary contraction (MVC), delayed onset muscle soreness (DOMS), creatine kinase (CK) activity, and interleukin-6 (IL-6) expression. The assessments were performed before exercise protocols, after 1 min, and 1, 24, 48, 72, and 96 h after the end of eccentric exercise protocol used to induce fatigue. LLLT was applied before eccentric exercise protocol with a cluster with five diodes, and dose of 10, 30, or 50 J (200 mW and 810 nm) in six sites of quadriceps.

RESULTS:

LLLT increased (p < 0.05) MVC from immediately after exercise to 24 h with 50 J dose, and from 24 to 96 h with 10 J dose. Both 10 J then 50 J dose decreased (p < 0.05) CK and IL-6 with better results in favor of 50 J dose. However, LLLT had no effect in decreasing DOMS. No differences (p > 0.05) were found for 30 J dose in any of the outcomes measured.

CONCLUSIONS:

Pre-exercise LLLT, mainly with 50 J dose, significantly increases performance and improves biochemical markers related to skeletal muscle damage and inflammation.

PMID:
27575834
DOI:
10.1089/pho.2015.3992
[Indexed for MEDLINE]

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