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World J Gastrointest Pathophysiol. 2016 Aug 15;7(3):276-82. doi: 10.4291/wjgp.v7.i3.276.

Pancreatic disorders in inflammatory bowel disease.

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Filippo Antonini, Giampiero Macarri, Department of Gastroenterology, A.Murri Hospital, Polytechnic University of Marche, 63900 Fermo, Italy.


An increased incidence of pancreatic disorders either acute pancreatitis or chronic pancreatitis has been recorded in patients with inflammatory bowel disease (IBD) compared to the general population. Although most of the pancreatitis in patients with IBD seem to be related to biliary lithiasis or drug induced, in some cases pancreatitis were defined as idiopathic, suggesting a direct pancreatic damage in IBD. Pancreatitis and IBD may have similar presentation therefore a pancreatic disease could not be recognized in patients with Crohn's disease and ulcerative colitis. This review will discuss the most common pancreatic diseases seen in patients with IBD.


Crohn’s disease; Exocrine pancreatic insufficiency; Extraintestinal manifestations; Inflammatory bowel disease; Pancreas; Pancreatitis; Ulcerative colitis

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