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Methods Enzymol. 2016;579:1-17. doi: 10.1016/bs.mie.2016.05.056. Epub 2016 Jul 5.

Direct Electron Detectors.

Author information

1
MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
2
MRC Laboratory of Molecular Biology, Cambridge, United Kingdom. Electronic address: rh15@mrc-lmb.cam.ac.uk.

Abstract

Direct electron detectors have played a key role in the recent increase in the power of single-particle electron cryomicroscopy (cryoEM). In this chapter, we summarize the background to these recent developments, give a practical guide to their optimal use, and discuss future directions.

KEYWORDS:

CMOS; DDD; DQE; Direct Electron; Electron microscopy; FEI; Gatan; MTF; Sensor; cryoEM

PMID:
27572721
DOI:
10.1016/bs.mie.2016.05.056
[Indexed for MEDLINE]

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