The authors report on a clinical study conducted in 1985/86 for evaluating the efficacy of Broncho-Vaxom in children with chronic bronchitis. They observed, during the Broncho-Vaxom therapy, a significant reduction in the number and severity of the acute episodes as well as the significant reduction of the use of antibiotics. They recommend the use of Broncho-Vaxom in chronic, recurrent respiratory infections.