Molecular characterisation of triple negative essential thrombocythaemia patients by platelet analysis and targeted sequencing

A Angona; C Fernández-Rodríguez; A Alvarez-Larrán; L Camacho; R Longarón; E Torres; S Pairet; C Besses; B Bellosillo

doi:10.1038/bcj.2016.75

Molecular characterisation of triple negative essential thrombocythaemia patients by platelet analysis and targeted sequencing

Blood Cancer J. 2016 Aug 26;6(8):e463. doi: 10.1038/bcj.2016.75.

Authors

A Angona^{1

2

3}, C Fernández-Rodríguez^{2

3}, A Alvarez-Larrán^{1

2

3}, L Camacho^{3

4}, R Longarón^{3

4}, E Torres⁴, S Pairet^{2

4}, C Besses^{1

3}, B Bellosillo^{3

4

5}

Affiliations

¹ Department of Haematology, Hospital del Mar, Barcelona, Spain.
² Universitat Autònoma de Barcelona, Barcelona, Spain.
³ Grup de Recerca Clínica Aplicada en Neoplàsies Hematològiques-IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
⁴ Department of Pathology, Hospital del Mar, Barcelona, Spain.
⁵ Universitat Pompeu Fabra, Barcelona, Spain.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Blood Platelets / metabolism*
Blood Platelets / pathology
Calreticulin / genetics
Child
Cohort Studies
Female
High-Throughput Nucleotide Sequencing
Humans
Janus Kinase 2 / genetics
Male
Middle Aged
Molecular Diagnostic Techniques
Polymorphism, Restriction Fragment Length
Real-Time Polymerase Chain Reaction
Receptors, Thrombopoietin / genetics
Sequence Analysis, DNA / methods*
Thrombocythemia, Essential / diagnosis*
Thrombocythemia, Essential / genetics*
Thrombocythemia, Essential / pathology
Transcriptome*
Young Adult

Substances

CALR protein, human
Calreticulin
Receptors, Thrombopoietin
MPL protein, human
JAK2 protein, human
Janus Kinase 2