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Biomed Khim. 2016 May;62(4):369-75. doi: 10.18097/PBMC20166204369.

[Composition and biological activity of triterpenes and steroids from Inonotus obliquus (chaga)].

[Article in Russian; Abstract available in Russian from the publisher]

Author information

1
Kazan National Research Technological University, Kazan, Russia.

Abstract

in English, Russian

Data on the chemical composition of triterpenic and steroid compounds, isolated from the chaga mushroom grown in natural environment or in a synthetic culture have been summarized. Special attention has been paid to the biological activity of chaga mushroom extracts and these particular compounds against various cancer cell lines in vitro and in vivo. This analysis has demonstrated some common features in inhibition of growth of various cell lines by chaga mushroom components. In this context, the most active are triterpene compounds containing OH group at C-22 and a side chain unsaturated bond.

KEYWORDS:

biological activity; chaga mushroom; in vitro; in vivo; steroids; triterpenes

PMID:
27562990
DOI:
10.18097/PBMC20166204369
[Indexed for MEDLINE]

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