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Rev Med Inst Mex Seguro Soc. 2016;54 Suppl 2:S202-9.

[Vitamin D deficiency associated with insulin resistance in medical residents].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

1
Departamento de Medicina Interna, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México. mnoyola.g@gmail.com.

Abstract

in English, Spanish

BACKGROUND:

Several studies have reported a correlation between vitamin D deficiency and insulin resistance; however, other clinical trials show that vitamin D supplementation do not normalize glucose and insulin levels. We designed a study to show if there is a correlation between serum vitamin D and the homeostatic model assessment 2 (HOMA 2).

METHODS:

It was designed a cross-sectional, descriptive, and analytical study, which included medical residents. They answered a questionnaire to record the time of sun exposure. We took anthropometric measurements, such as weight, height, and waist circumference, as well as some serum levels: serum vitamin D, serum insulin, fasting blood glucose, triglycerides and high-density lipoprotein-cholesterol. The correlation between serum vitamin D and HOMA 2 was determined by the correlation of Pearson; it was considered significant a p < 0.05.

RESULTS:

The decreased serum vitamin D levels did not correlate with high concentrations of HOMA 2 (r = -0.11, p = 0.34). A negative correlation between vitamin D levels and index size waist was observed (r = -0.27, p = 0.025). HOMA 2 was positively correlated with waist size index (r = 0.23, p = 0.05) and triglycerides (r = 0.61, p = 0.01) and negatively with high density lipoprotein-cholesterol (r = -0.26, p = 0.02).

CONCLUSIONS:

We couldn't show the correlation between vitamin D deficiency and insulin resistance.

KEYWORDS:

Insulin resistance; Vitamin D deficiency

PMID:
27561026
[Indexed for MEDLINE]

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