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Optom Vis Sci. 2016 Sep;93(9):1052-4. doi: 10.1097/OPX.0000000000000978.

Animal Studies and the Mechanism of Myopia-Protection by Light?

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*PhD Centre for Research in Therapeutic Solutions, Faculty of Education, Science, Technology and Mathematics, University of Canberra, Australian Capital Territory, Australia.


Epidemiological studies have demonstrated that spending time outdoors during your childhood is protective against the development of myopia. It has been hypothesized that this protective effect is associated with light-induced increases in retinal dopamine levels, a critical neuromodulator that has long been postulated to be involved in the regulation of ocular growth. This paper, along with the paper entitled "What do animal studies tell us about the mechanism of myopia-protection by light?" discusses the evidence provided by animal models for this hypothesis.

[Indexed for MEDLINE]

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