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Curr Urol Rep. 2016 Oct;17(10):72. doi: 10.1007/s11934-016-0629-8.

Novel Uses for the Anabolic Androgenic Steroids Nandrolone and Oxandrolone in the Management of Male Health.

Author information

1
McMaster Institute of Urology, Hamilton, ON, Canada.
2
Men's Health Center, 8240 Naab Road, Suite #220, Indianapolis, IN, 46260, USA. jkovac@urologyin.com.

Abstract

There has recently been renewed interest in novel clinical applications of the anabolic-androgenic steroid (AAS) testosterone and its synthetic derivatives, particularly given with the rising popularity of testosterone supplementation therapy (TST) for the treatment of male hypogonadism. In this manuscript, we provide a brief review of the history of AAS and discuss clinical applications of two of the more well-known AAS: nandrolone and oxandrolone. Both agents exhibit favorable myotrophic/androgenic ratios and have been investigated for effectiveness in numerous disease states. We also provide a brief synopsis of selective androgen receptor modulators (SARMs) and postulate how these orally active, non-aromatizing, tissue-selective agents might be used in contemporary andrology. Currently, the applications of testosterone alternatives in hypogonadism are limited. However, it is tempting to speculate that these agents may one day become accepted as alternatives, or adjuncts, to the treatment of male hypogonadism.

KEYWORDS:

Androgenic anabolic steroids; Hypogonadism; Nandrolone; Oxandrolone; SARMS

PMID:
27535042
DOI:
10.1007/s11934-016-0629-8
[Indexed for MEDLINE]

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