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FEBS Lett. 1989 Jul 3;250(2):231-4.

Isolation and structure of corazonin, a cardioactive peptide from the American cockroach.

Author information

1
Department of Biological Organic Chemistry, Centro de Investigación y Desarrollo, CSIC, Barcelona, Spain.

Abstract

Corazonin, a new cardioaccelerating peptide, has been isolated from the corpora cardiaca of the American cockroach, Periplaneta americana, and its structure determined to be Glp-Thr-Phe-Gln-Tyr-Ser-Arg-Gly-Trp-Thr-Asn-amide. The peptide stimulated heart beat at concentrations as low as 0.2 nM, which makes it the most potent insect cardioactive neuropeptide.

PMID:
2753132
DOI:
10.1016/0014-5793(89)80727-6
[Indexed for MEDLINE]
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