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Oncotarget. 2016 Aug 30;7(35):56147-56152. doi: 10.18632/oncotarget.11269.

OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research.

Han SK1, Lee D1, Lee H1, Kim D1, Son HG1, Yang JS2, Lee SV1,3,4, Kim S1,3,4.

Author information

1
Department of Life Sciences, Pohang University of Science and Technology, Pohang, Korea.
2
EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), Barcelona, Spain.
3
Department of IT Convergence and Engineering, Pohang University of Science and Technology, Pohang, Korea.
4
School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Korea.

Abstract

Online application for survival analysis (OASIS) has served as a popular and convenient platform for the statistical analysis of various survival data, particularly in the field of aging research. With the recent advances in the fields of aging research that deal with complex survival data, we noticed a need for updates to the current version of OASIS. Here, we report OASIS 2 (http://sbi.postech.ac.kr/oasis2), which provides extended statistical tools for survival data and an enhanced user interface. In particular, OASIS 2 enables the statistical comparison of maximal lifespans, which is potentially useful for determining key factors that limit the lifespan of a population. Furthermore, OASIS 2 provides statistical and graphical tools that compare values in different conditions and times. That feature is useful for comparing age-associated changes in physiological activities, which can be used as indicators of "healthspan." We believe that OASIS 2 will serve as a standard platform for survival analysis with advanced and user-friendly statistical tools for experimental biologists in the field of aging research.

KEYWORDS:

healthspan; maximum lifespan; statistics; survival; web-service

PMID:
27528229
PMCID:
PMC5302902
DOI:
10.18632/oncotarget.11269
[Indexed for MEDLINE]
Free PMC Article

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