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J Magn Reson Imaging. 2017 Apr;45(4):1076-1081. doi: 10.1002/jmri.25430. Epub 2016 Aug 16.

Fat-suppressed T2 mapping of femoral cartilage in the porcine knee joint: A comparison with conventional T2 mapping.

Author information

1
Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Korea.

Abstract

PURPOSE:

To investigate the effect of fat suppression on T2 mapping of the articular cartilage in the porcine knee joint using magnetic resonance imaging (MRI).

MATERIALS AND METHODS:

Eleven porcine knee joints were harvested en bloc with intact capsules. We performed T2 mapping of the articular cartilage in the medial femoral condyle at 3T either with (fat-suppressed T2 mapping) or without (conventional T2 mapping) fat suppression in the sagittal plane under two frequency-encoding directions: from superior to inferior (SI) and inferior to superior (IS). Two observers measured the T2 values of the medial femoral condyle cartilage in four regions: in the anterior oblique, central horizontal, posterior oblique, and posterior vertical portions. We evaluated reproducibility of the fat-suppressed and conventional T2 mapping by changing the frequency-encoding direction.

RESULTS:

The mean T2 values of fat-suppressed T2 mapping were significantly lower than those of conventional T2 mapping for five of eight comparisons (P < 0.017). The mean T2 values between fat-suppressed T2 -SI and fat-suppressed T2 -IS did not differ significantly in any region (P = 0.077-0.873). However, the mean T2 values of conventional T2 -SI were significantly lower compared with conventional T2 -IS in three of the regions (P < 0.05). The intraclass correlation coefficient (ICC) between the two fat-suppressed T2 maps was higher than the ICC between the two conventional T2 maps (0.276-0.800 vs. -0.032-0.455) for three regions.

CONCLUSION:

Compared with conventional T2 mapping, fat-suppressed T2 mapping provides lower T2 values of the articular cartilage and more reproducible results for the porcine knee joint.

LEVEL OF EVIDENCE:

2 J. Magn. Reson. Imaging 2017;45:1076-1081.

KEYWORDS:

T2 mapping; articular cartilage; chemical shift artifact; fat suppression

PMID:
27527688
DOI:
10.1002/jmri.25430
[Indexed for MEDLINE]

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