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Avicenna J Phytomed. 2016 Jul-Aug;6(4):458-267.

The effect of Allium sativum (Garlic) extract on infectious bronchitis virus in specific pathogen free embryonic egg.

Author information

1
Department of Avian Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
2
Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.

Abstract

OBJECTIVE:

Garlic is a plant has been used as a flavor, and anti-microbial and anti-diarrheal agent. Infectious bronchitis virus (IBV) is a coronavirus. The available vaccines against IBV cannot cover new variants. This study evaluated the inhibitory effects of garlic extract on IBV.

MATERIALS AND METHODS:

The constituents of garlic extract were detected by gas chromatography. This study was done in four groups of embryonic SPF eggs; first group was used for virus titration; second group received the mixture of different virus titration and constant amount of garlic extract; third group received 10(-3) titration of virus and after 8 hr received garlic extract and the last group received different dilutions of garlic extract.

RESULTS:

Based on our results, in the second group, IBV vaccine strain (4/91) at all titration and M41 in 10(-2) and 10(-3) titration and in the third group both variants of virus the embryonic Index (EI) was significantly increased.

CONCLUSION:

The garlic extract had inhibitory effects on IBV in the chickens embryo.

KEYWORDS:

Antiviral; Embryonic Index; Garlic extract; Herbal medicine; Infectious Bronchitis Virus

PMID:
27516987
PMCID:
PMC4967842

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